Tutorial

The usage of LncRNADisease v3.0 database is as follows

1. Overview of LncRNADisease v3.0
     1. Main functions of the database are provided in the menu bar.
     2. Main statistics of the database.
     3. Updated news about the database.
     4. Distribution of all experimental data in the database.
     5. Database citation.


2. Search Database
     The SEARCH page is displayed as follow
     1. Select a category: Three choices are provided.
     2. Input a keyword (e.g. H19) or semicolon-separated multiple keywords (e.g. H19;HOTAIR)corresponding to the selected category.
     3. Five categories provided to filter results.

Notes:
     ① Use NCBI Gene/Disease Ontology/MeSH to normalize your input information.
     ② If you got no result or too few results, you may shorten your keywords.


3. Search Result
The Result page is displayed as follow.
In the Result page, all associations are listed with basic information including Symbol, Category, Species, Disease Name, Detection Method, Prediction Method and Score.
     1. Total page and amount of results.
     2. Click to turn the page.
     3. Click to link to the Entry Detail page.
     4. Click to download the search result.


4. Browse Database
The BROWSE page is displayed as follow.
Associations can be displayed selectively according to selected conditions.
     1. Browse by different categories.
     2. Database items.


5. Entry Detail
The Entry Detail page is displayed as follow.
In the Entry Detail page, you can get information including General Information, ncRNA Information, ncRNA Association Statistics, Disease Information, Disease Association Statistics, Evidence Support and Reference. Here, the cinilical significance is newly increased and corresponding description can be found in Reference.
    1. Click Ensembl ID, Ensembl Transcript ID, Entrez Gene, NONCODE ID, and RefSeq Asscession to get more detailed information in external databases.
     2. Click More Information to browse and download the basic information of all the associated diseases of this ncRNA.
     3. Click More Information to browse all causal associations of this ncRNA.
     4. Browse Disease Ontology ID/MeSH to get more detailed information in Disease Ontology/MeSH.
     5. Click More Information to browse and download the basic information of all the associated ncRNAs of this disease.
     6. Click More Information to browse all causal associations of this disease.
     7. Click PubMed ID to get more detailed information in NCBI.


6. About Us
This database is hosted by Cui Lab, Department of Biomedical Informatics, Center for Noncoding RNA Medicine, State Key Laboratory of Vascular Homeostasis and Remodeling, School of Basic Medical Sciences, Peking University
If you have any questions or suggestions about our database, please don’t hesitate to contact us.
Email: cuiqinghua@bjmu.edu.cn
Database Administrator: ccm328@bjmu.edu.cn